Sequence — Evolution — Function: Computational Approaches in Comparative GenomicsSpringer Science & Business Media, 2013 M06 29 - 462 páginas Sequence - Evolution - Function is an introduction to the computational approaches that play a critical role in the emerging new branch of biology known as functional genomics. The book provides the reader with an understanding of the principles and approaches of functional genomics and of the potential and limitations of computational and experimental approaches to genome analysis. Key topics covered in this textbook are: |
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... comparison 4.2.3 . Protein sequence complexity . Compositional bias 4.3 . Algorithms for sequence alignment and similarity search ........ 4.3.1 . The basic alignment concepts and principal algorithms .. 4.3.2 . Sequence database search ...
... comparisons for functional annotation of predicted proteins . We introduce the most common sequence similarity search methods and discuss the ways to automate the searches and increase search sensitivity , while minimizing the error ...
... comparison to solve the mystery of the Origin of Life . Little did he know that his entire career in science would be dedicated to this very objective : understanding evolution through comparisons of genes , genomes , and proteins . Now ...
... Hypothetical protein * the data from the NCBI Entrez Genomes web site , http://www.ncbi.nlm.nih.gov/cgi-bin/Entrez/altik?gi=10119&db=Genome A comparison of Table 1.1 with the original paper by 1. Genomics from Phage to Human 5.
Computational Approaches in Comparative Genomics Eugene V. Koonin, Michael Galperin. A comparison of Table 1.1 with the original paper by Sanger et al . [ 742 ] shows that there is actually not much to add to the gene annotations . The ...
Contenido
3 | |
25 | |
Information Sources for Genomics 51 | 50 |
Principles and Methods of Sequence Analysis | 111 |
Genome Annotation and Analysis | 193 |
Comparative Genomics and New Evolutionary | 227 |
Genomes and the Protein Universe | 357 |
Peering through the crystal ball 371 | 370 |
Appendices | 381 |
References | 403 |
Index | 457 |
Otras ediciones - Ver todas
Sequence — Evolution — Function: Computational Approaches in Comparative ... Eugene Koonin,Michael Y. Galperin Vista previa limitada - 2002 |
Sequence — Evolution — Function: Computational Approaches in Comparative ... Eugene Koonin,Michael Y. Galperin Sin vista previa disponible - 2010 |
Sequence — Evolution — Function: Computational Approaches in Comparative ... Eugene Koonin,Michael Y. Galperin Sin vista previa disponible - 2013 |