Sequence — Evolution — Function: Computational Approaches in Comparative GenomicsSpringer Science & Business Media, 2013 M06 29 - 462 páginas Sequence - Evolution - Function is an introduction to the computational approaches that play a critical role in the emerging new branch of biology known as functional genomics. The book provides the reader with an understanding of the principles and approaches of functional genomics and of the potential and limitations of computational and experimental approaches to genome analysis. Key topics covered in this textbook are: |
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... encoded in these genes can be accomplished only by combining powerful computational tools with a variety of experimental approaches from the arsenals of biochemistry , molecular biology , genetics and cell biology . Linking sequence to ...
... encoded proteins . Such an analysis proves valuable for many branches of biology , in large part , because it assists in classification and prioritization of the targets for future experimental research . Computations on genomes are ...
... . Finally , a terminological point related to the last issue : throughout the book , we rather freely substitute proteins for the genes that encode them by talking about duplications , mutations and other evolutions of proteins . This xii.
... encoded in any prokaryotic genome [ 827 ] . At present this fraction seems to be somewhat lower for some of the eukaryotes , but only because the taxonomic density of genome sequencing so far has been insufficient . Indeed , in the ...
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Contenido
3 | |
25 | |
Information Sources for Genomics 51 | 50 |
Principles and Methods of Sequence Analysis | 111 |
Genome Annotation and Analysis | 193 |
Comparative Genomics and New Evolutionary | 227 |
Genomes and the Protein Universe | 357 |
Peering through the crystal ball 371 | 370 |
Appendices | 381 |
References | 403 |
Index | 457 |
Otras ediciones - Ver todas
Sequence — Evolution — Function: Computational Approaches in Comparative ... Eugene Koonin,Michael Y. Galperin Vista previa limitada - 2002 |
Sequence — Evolution — Function: Computational Approaches in Comparative ... Eugene Koonin,Michael Y. Galperin Sin vista previa disponible - 2010 |
Sequence — Evolution — Function: Computational Approaches in Comparative ... Eugene Koonin,Michael Y. Galperin Sin vista previa disponible - 2013 |