Sequence — Evolution — Function: Computational Approaches in Comparative GenomicsSpringer Science & Business Media, 2013 M06 29 - 462 páginas Sequence - Evolution - Function is an introduction to the computational approaches that play a critical role in the emerging new branch of biology known as functional genomics. The book provides the reader with an understanding of the principles and approaches of functional genomics and of the potential and limitations of computational and experimental approaches to genome analysis. Key topics covered in this textbook are: |
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... eukaryotic genomes . We show , however , that the main principles remain the same for comparative genomics in general . The book starts with a brief overview of the history of genomics . We list the completed and ongoing genome ...
... eukaryotic genomes ?, ( ii ) how accurate was the sequence itself and the original gene assignment ?, and ( iii ) how much more have we learned about functions of λ genes in the past 20 years ? The answer to the first question is ...
... eukaryotes Exo Bacteria , archaea , ( RedX ) eukaryotes , viruses Structure , domain architecture A modified P - loop ATPase domain , distantly related to a vast class of helicases ClpP protease domain Consists of an N - terminal JAB ...
... eukaryotic genome ( yeast ) completely sequenced Introduction of gapped BLAST and PSI - BLAST COGS : Evolutionary classification of proteins from [ 290 ] [ 22 ] [ 828 ] complete genomes 1998 Worm genome , the first multicellular genome ...
... eukaryotes ) were completely sequenced and available in public databases . In the three parts of Table 1.4 , the completely sequenced bacterial , archaeal , and eukaryotic genomes 1. Genomics from Phage to Human 13 and the astonishing ...
Contenido
3 | |
25 | |
Information Sources for Genomics 51 | 50 |
Principles and Methods of Sequence Analysis | 111 |
Genome Annotation and Analysis | 193 |
Comparative Genomics and New Evolutionary | 227 |
Genomes and the Protein Universe | 357 |
Peering through the crystal ball 371 | 370 |
Appendices | 381 |
References | 403 |
Index | 457 |
Otras ediciones - Ver todas
Sequence — Evolution — Function: Computational Approaches in Comparative ... Eugene Koonin,Michael Y. Galperin Vista previa limitada - 2002 |
Sequence — Evolution — Function: Computational Approaches in Comparative ... Eugene Koonin,Michael Y. Galperin Sin vista previa disponible - 2010 |
Sequence — Evolution — Function: Computational Approaches in Comparative ... Eugene Koonin,Michael Y. Galperin Sin vista previa disponible - 2013 |