Sequence — Evolution — Function: Computational Approaches in Comparative GenomicsSpringer Science & Business Media, 2013 M06 29 - 462 páginas Sequence - Evolution - Function is an introduction to the computational approaches that play a critical role in the emerging new branch of biology known as functional genomics. The book provides the reader with an understanding of the principles and approaches of functional genomics and of the potential and limitations of computational and experimental approaches to genome analysis. Key topics covered in this textbook are: |
Dentro del libro
Resultados 1-5 de 90
... sequencing 1.3 . Basic questions of comparative genomics .... Chapter 2. The Evolutionary Concept in Genetics and Genomics ... 2.1 . Similarity , homology , divergence and convergence 2.1.2 . Conservation of protein sequence and ...
... sequence comparison 4.2.3 . Protein sequence complexity . Compositional bias 4.3 . Algorithms for sequence alignment and similarity search ........ 4.3.1 . The basic alignment concepts and principal algorithms .. 4.3.2 . Sequence ...
... sequence and using sequence comparisons for functional annotation of predicted proteins . We introduce the most common sequence similarity search methods and discuss the ways to automate the searches and increase search sensitivity ...
... similarity of membrane organization and energy - transducing processes in bacteria , mitochondria and chloroplasts . He became interested in the apparent paradox : if survival of any living cells depends on the integrity of its ...
... sequence similarity that allowed the identification of homologous ( orthologous ) genes , but also , in part , the order of these genes in their genomes [ 7,56,335 ] . Subsequent systematic studies have revealed a complex network of ...
Contenido
3 | |
25 | |
Information Sources for Genomics 51 | 50 |
Principles and Methods of Sequence Analysis | 111 |
Genome Annotation and Analysis | 193 |
Comparative Genomics and New Evolutionary | 227 |
Genomes and the Protein Universe | 357 |
Peering through the crystal ball 371 | 370 |
Appendices | 381 |
References | 403 |
Index | 457 |
Otras ediciones - Ver todas
Sequence — Evolution — Function: Computational Approaches in Comparative ... Eugene Koonin,Michael Y. Galperin Vista previa limitada - 2002 |
Sequence — Evolution — Function: Computational Approaches in Comparative ... Eugene Koonin,Michael Y. Galperin Sin vista previa disponible - 2010 |
Sequence — Evolution — Function: Computational Approaches in Comparative ... Eugene Koonin,Michael Y. Galperin Sin vista previa disponible - 2013 |