Handbook of the Biology of AgingEdward J. Masoro, Steven N. Austad Elsevier, 2011 M04 28 - 680 páginas The Handbook of the Biology of Aging, Sixth Edition, provides a comprehensive overview of the latest research findings in the biology of aging. Intended as a summary for researchers, it is also adopted as a high level textbook for graduate and upper level undergraduate courses. The Sixth Edition is 20% larger than the Fifth Edition, with 21 chapters summarizing the latest findings in research on the biology of aging. The content of the work is virtually 100% new. Though a selected few topics are similar to the Fifth Edition, these chapters are authored by new contributors with new information. The majority of the chapters are completely new in both content and authorship. The Sixth Edition places greater emphasis and coverage on competing and complementary theories of aging, broadening the discussion of conceptual issues. Greater coverage of techniques used to study biological issues of aging include computer modeling, gene profiling, and demographic analyses. Coverage of research on Drosophilia is expanded from one chapter to four. New chapters on mammalian models discuss aging in relation to skeletal muscles, body fat and carbohydrate metabolism, growth hormone, and the human female reproductive system. Additional new chapters summarize exciting research on stem cells and cancer, dietary restriction, and whether age related diseases are an integral part of aging. The Handbook of the Biology of Aging, Sixth Edition is part of the Handbooks on Aging series, including Handbook of the Psychology of Aging and Handbook of Aging and the Social Sciences, also in their 6th editions. |
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Página viii
... Tatar I. Introduction 415 II. JH and 20E: Two Major Insect Hormones 416 III. Effects of JH and 20E on Drosophila Aging 418 IV. V. VI. VII. Candidate Genes Affecting Life Span Through JH and 20E Signaling 422 Hormones, Nutrition, and ...
... Tatar I. Introduction 415 II. JH and 20E: Two Major Insect Hormones 416 III. Effects of JH and 20E on Drosophila Aging 418 IV. V. VI. VII. Candidate Genes Affecting Life Span Through JH and 20E Signaling 422 Hormones, Nutrition, and ...
Página xiii
... Tatar (415), Division of Biology and Medicine, Department of Ecology and Evolutionary Biology, Brown University, Providence, RI 02916 John Tower (400), Molecular and Computational Biology Program, Department of Biology, University of ...
... Tatar (415), Division of Biology and Medicine, Department of Ecology and Evolutionary Biology, Brown University, Providence, RI 02916 John Tower (400), Molecular and Computational Biology Program, Department of Biology, University of ...
Página 18
... (Tatar et al., 1993). Interestingly, the failure kinetics of manufactured products (steel samples, industrial relays, and motor heat insulators) also demonstrates the same “nonaging” pattern at the end of their “life span” (Economos ...
... (Tatar et al., 1993). Interestingly, the failure kinetics of manufactured products (steel samples, industrial relays, and motor heat insulators) also demonstrates the same “nonaging” pattern at the end of their “life span” (Economos ...
Página 36
... Tatar, M. (2002). The aging baboon: comparative demography in a non-human primate. Proceedings of the National Academy of Sciences of the USA, 99, 9591–9595. Brooks, A., Lithgow, G. J., & Johnson, T. E. (1994). Mortality rates in a ...
... Tatar, M. (2002). The aging baboon: comparative demography in a non-human primate. Proceedings of the National Academy of Sciences of the USA, 99, 9591–9595. Brooks, A., Lithgow, G. J., & Johnson, T. E. (1994). Mortality rates in a ...
Página 42
... Tatar, M., Carey, J. R., & Vaupel, J. W. (1993). Long-term cost of reproduction with and without accelerated senescence in Callosobruchus maculatus: analysis of age-specific mortality. Evolution, 47, 1302–1312. United Nations (1967) ...
... Tatar, M., Carey, J. R., & Vaupel, J. W. (1993). Long-term cost of reproduction with and without accelerated senescence in Callosobruchus maculatus: analysis of age-specific mortality. Evolution, 47, 1302–1312. United Nations (1967) ...
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Academy of Sciences activity adult age-associated age-related age-specific alleles analysis animals apoptosis associated biology of aging Caenorhabditis elegans caloric restriction cancer cellular colleagues Curtsinger damage decline decrease disease Drosophila melanogaster effects evolution evolutionary Experimental Gerontology extend life span female fibers flies function gene expression gene expression changes genetic genome Gerontology Gompertz growth factor growth hormone Hormesis human IGF-I increased life span insulin signaling insulin-like growth insulin-like growth factor interactions Journal of Gerontology juvenile hormone kinase levels lifespan long-lived longevity male Masoro Mechanisms of Ageing metabolism mice microarray mitochondrial Molecular mortality rates mouse mutations National Academy Nature neurons organisms overexpression oxidative stress pathway percent phenotypes physiological pleiotropy population Promislow protein QTLs rats receptor regulation reproductive Research response role senescence Sir2 SIRT1 sirtuins skeletal muscle species stem cells stress resistance studies survival Tatar telomere theory tion tissue transcription factor worms yeast