Handbook of the Biology of AgingEdward J. Masoro, Steven N. Austad Elsevier, 2011 M04 28 - 680 páginas The Handbook of the Biology of Aging, Sixth Edition, provides a comprehensive overview of the latest research findings in the biology of aging. Intended as a summary for researchers, it is also adopted as a high level textbook for graduate and upper level undergraduate courses. The Sixth Edition is 20% larger than the Fifth Edition, with 21 chapters summarizing the latest findings in research on the biology of aging. The content of the work is virtually 100% new. Though a selected few topics are similar to the Fifth Edition, these chapters are authored by new contributors with new information. The majority of the chapters are completely new in both content and authorship. The Sixth Edition places greater emphasis and coverage on competing and complementary theories of aging, broadening the discussion of conceptual issues. Greater coverage of techniques used to study biological issues of aging include computer modeling, gene profiling, and demographic analyses. Coverage of research on Drosophilia is expanded from one chapter to four. New chapters on mammalian models discuss aging in relation to skeletal muscles, body fat and carbohydrate metabolism, growth hormone, and the human female reproductive system. Additional new chapters summarize exciting research on stem cells and cancer, dietary restriction, and whether age related diseases are an integral part of aging. The Handbook of the Biology of Aging, Sixth Edition is part of the Handbooks on Aging series, including Handbook of the Psychology of Aging and Handbook of Aging and the Social Sciences, also in their 6th editions. |
Dentro del libro
Resultados 1-5 de 64
Página 23
... worms kept in controlled environmental condi- tions (Herndon et al., 2002). The graph shown in Figure 1.8 depicts mortality trajectories for five systems with different degrees of redundancy. System 1 has only one unique element (no ...
... worms kept in controlled environmental condi- tions (Herndon et al., 2002). The graph shown in Figure 1.8 depicts mortality trajectories for five systems with different degrees of redundancy. System 1 has only one unique element (no ...
Página 63
... worms, flies, spiders, dogs, and fish (Weindruch & Walford, 1988). Although there are exceptional species that do not fit the DR paradigm, namely mayflies and guppies (Carey et al., 2005; Reznick et al., 2004), the broad conservation of ...
... worms, flies, spiders, dogs, and fish (Weindruch & Walford, 1988). Although there are exceptional species that do not fit the DR paradigm, namely mayflies and guppies (Carey et al., 2005; Reznick et al., 2004), the broad conservation of ...
Página 64
... worms uncovered single mutations that could dramatically extend life span , seemingly contradicting the complexity of aging . Friedman and Johnson's discovery ( 1988 ) of age - 1 mutations that extend worm life span was seminal . Around ...
... worms uncovered single mutations that could dramatically extend life span , seemingly contradicting the complexity of aging . Friedman and Johnson's discovery ( 1988 ) of age - 1 mutations that extend worm life span was seminal . Around ...
Página 67
... worms, flies, and yeast (Krystal & Yu, 1994; Weindruch & Walford, 1988). Today, it is generally accepted that DR implemented during only the first few months of life of a rodent can have small longevity benefits, but the most ...
... worms, flies, and yeast (Krystal & Yu, 1994; Weindruch & Walford, 1988). Today, it is generally accepted that DR implemented during only the first few months of life of a rodent can have small longevity benefits, but the most ...
Página 72
... worms , flies , fish , spiders - it is a case of overfeeding the control organisms . In the wild , yeast and flies often have an abundance of food , far more than is supplied in the lab . Another argument against DR being a laboratory ...
... worms , flies , fish , spiders - it is a case of overfeeding the control organisms . In the wild , yeast and flies often have an abundance of food , far more than is supplied in the lab . Another argument against DR being a laboratory ...
Otras ediciones - Ver todas
Términos y frases comunes
Academy of Sciences activity adult age-associated age-related age-specific aging process alleles analysis animals apoptosis associated biology of aging Caenorhabditis elegans caloric restriction cancer cellular colleagues Curtsinger damage decline decrease disease Drosophila melanogaster effects evolution evolutionary Experimental Gerontology female fibers flies function gene expression gene expression changes genetic genome Gerontology Gompertz growth factor growth hormone Hormesis human IGF-I increased life span insulin signaling insulin-like growth insulin-like growth factor interactions Journal of Gerontology juvenile hormone kinase levels lifespan long-lived longevity male Masoro Mechanisms of Ageing metabolism mice microarray mitochondrial Molecular mortality rates mouse mutations National Academy Nature nematodes neurons organisms overexpression oxidative stress percent phenotypes physiological pleiotropy population Promislow protein QTLs rats receptor regulation reproductive Research response role senescence Sir2 SIRT1 sirtuins skeletal muscle species stem cells stress resistance studies survival Tatar telomere theory tion tissue transcription factor worms yeast