Bioinformatics and Functional Genomics

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John Wiley & Sons, 2005 M03 4 - 792 páginas
Wiley is proud to announce the publication of the first ever broad-based textbook introduction to Bioinformatics and Functional Genomics by a trained biologist, experienced researcher, and award-winning instructor. In this new text, author Jonathan Pevsner, winner of the 2001 Johns Hopkins University "Teacher of the Year" award, explains problem-solving using bioinformatic approaches using real examples such as breast cancer, HIV-1, and retinal-binding protein throughout. His book includes 375 figures and over 170 tables. Each chapter includes: Problems, discussion of Pitfalls, Boxes explaining key techniques and math/stats principles, Summary, Recommended Reading list, and URLs for freely available software. The text is suitable for professionals and students at every level, including those with little to no background in computer science.
 

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Contenido

PART II GENOMEWIDE ANALYSIS OF RNA AND PROTEIN
155
PART III GENOME ANALYSIS
395
Epilogue
695
Appendix GCG for Protein and DNA Analysis
697
Glossary
717
Solutions to SelfTest Quizzes
735
Subject Index
737
Author Index
753
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Acerca del autor (2005)

Jonathan Pevsner received his Ph.D. in Pharmacology and Molecular Sciences at the Johns Hopkins School of Medicine (1989). There, he identified an odorant-binding protein in nasal secretions. He completed postdoctoral training as a Helen Hay Whitney fellow in the Department of Molecular Physiology at the Stanford University Medical Center. At Stanford he identified proteins that function in neurotransmitter release at nerve terminals. In 1995 he joined the faculty in the Department of Neurology at the Kennedy Krieger Institute and the Department of Neuroscience at the Johns Hopkins School of Medicine. He began teaching bioinformatics in 1996, and introduced a ten-week course in 2000. In 2001 the graduate students voted him Teacher of the Year, and in 2003 the Johns Hopkins faculty gave him the Professor’s Award for Excellence in Teaching. His lab studies the molecular basis of childhood neurological disorders including autism and Down Syndrome, and develops bioinformatics software.

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