KANSAS DEPARTMENT.

A Statement of the Situation in Kansas Regarding the Pure Food and Drugs Law and Proprietaries.

BY L. E. SAYRE.

Much has been said of late regarding the requirements of the Kansas Food and Drugs Law, and an all leged conflict between the present administration and the jobbers doing business in the State of Kansas, and the writer has been asked to make a statement concerning this.

In the outset it should be said that many statements have been made which have represented the case much stronger than the facts warrant. It has been said, for example, that the Kansas inspectors have notified certain manufacturers that they would not be permitted to sell certain products under their present label, etc. This has aroused, of course, some disturbance and from what can be learned has caused a flood of letters to come into the department in Topeka, protesting against such alleged ruling on the part of any of the officials of the department. It is not surprising that exaggerations regarding the question of misbranding are likely to be made, and these do not help matters in the administration of the drug law. It is to be stated at the outset that it is to the credit of the executive head, Dr. S. J. Crumbine, that he and his Board are in perfect harmony with the officials of the Proprietary Association, and it is believed that there will be no needless trouble arising between the two.

Geo. L. Douglass, who is well known as the counsel for the Proprietary Association, has expressed himself to the effect that the Kansas law, in regard to the misbranding of drugs, is substantially the same as the National law, and he has also expressed himself that he believed Dr. Crumbine, the Kansas Chief Food and Drug Inspector, to be a fair official, who does not desire to make any needless trouble for the drug trade. Dr. Crumbine says, however, that there is a great deal of old stock of proprietary medicine still being sold to the retailers in Missouri and Kansas, which has never been

re-labeled, much of which does not conform to the provisions of the state law. He urges that manufacturers either recall this old stock from the jobbers or have it relabeled at once in conformity with the state law, so that no more of it will pass into the hands of the retailers in its present condition.

Mr. Douglass has expressed himself that this is a very reasonable position, and urges that it be complied with at once.

As to the cases which involve the use of the word "cure" there is no question about it that there is a reasonable ground for difference of opinion, and as to this class of cases it is probable that the action regarding the test cases, commenced by the Federal Government in the District of Columbia, will bring about a clear understanding and will correct any difference of

opinion which may now exist. It should be stated that the use of the word "cure," where it is used as a part of the name and where its use occurs in a "reasonable sense" is one that is likely to lead to controversy, and it is gratifying to state that the department in Kansas is likely to take no further action in the matter pending a final decision of the court in reference to this vexed question.

It is to be noted, however, in this connection that there have been a number of glaring cases of misbranding shown by Kansas Board examination. Preparations, for example, for "summer complaint in children, cholera infantum, etc.", which reveal in the sedimentary substance a fungus growth (penicillium), and in the liquid, bacteria of all sorts, (sphers, rods, etc.) Such a deteriorated preparation, of course, is misbranded and is decidedly illegal. A vermifuge remedy is recommended for night sweats as well as various other ailments. A label states that the preparation "always cures colic, cholera morbus, diarrhoea, and all summer complaints." Numerous preparations are stated to be "positive cures" for from fourteen to twenty different ailments and painful afflictions. The following list of statements is made from labels, wrappers and printed matter on cartons, etc., and is taken at random:

"A positive cure for all diseases of the liver and kidneys." "An internal remedy for the cure of," among other ailments, "ring worm," (a parasitic disease, only relieved by external remedies.) A nerve remedy claims to "cure" twenty-three different ailments, several of which are considered incurable. "A permanent cure for all piles, ulcers," etc. "A positive cure for all diseases of the head." "A positive cure for every form of skin and blood disease." A statement to the effect that "its curative properties are never failing in rheumatism" and thirteen other complaints, including "salt rheum and tetter." A Wahoo remedy claims to be a "positive cure" for seventeen different ailments; this article contains no alcohol and but one per cent of total solids, aloes being a prominent constituent. A remedy claims to "cure" twenty-five different diseased conditions, including "diptheria, dyspepsia," etc.

All these statements point to glaring declarations which violate the spirit if not the letter of the law, and it is doubtless about this class of preparations and the accompanying literature that the alleged conflict has arisen. The stir about these only shows that Kansas is "getting busy."

If I may be pardoned for a little reflection, which may not be out of place in connection with this subject, I would say with regard to these antiquated and worn out therapeutic declarations belonging to the Haarlem Oil period, that they are, in the present day of medical progress, to say the least, offensive. Any one who is in sympathy with the present must realize that medicine knows no pause in progress and development, and he who is inactive and not alert in catching the spirit of this progress must be overthrown.

There Are lots of wise men-until you get next to them.

THERAPEUTICS FOR PHARMACISTS.

Gonorrhea Not a Minor Ailment.-The Philadelphia Branch of the American Pharmaceutical Association met February 4, and devoted the evening to a discussion of "The Responsibilities of the Retail Druggist in the Spread of the Great Black Plague."

The pharmacists of Philadelphia, appreciating the seriousness and the importance of the subject under discussion, were well represented and it was generally

admitted that those present were amply repaid by the interesting nature of the information that was given them.

The subject proper was introduced by Dr. Henry Beates, Jr., who discussed "The Relation of Medical Practice Acts to Contagious and Infectious Diseases." He called particular attention to the fact that in populous communities the so-called fundamental privileges or rights of the individual must of necessity be subordinated to the welfare of the community as a whole.

He further called attention to the generally accepted

definitions for what is understood by "practice of medicine" and pointed out that the usually accepted right of "self medication" is not permissable for persons suffering from a contagious or infectious disease, particularly when the health and even the lives of others may be in jeopardy.

Dr. A. A. Uhle, assistant instructor in Genito-Urinary Diseases at the University of Pennsylvania, presented a rather exhaustive paper on "Gonorrhea, Its Nature, Prevalency, Recognition and Treatment," in the course of which he quoted a number of rather interesting statistics as to the prevalency of this disease and the time and money loss that it involves. He also I called attention to the ease with which this disease may be spread and the difficulties that beset the proper diagnosis and the successful treatment of it, even in the hands of physicians who devote all of their time to its study.

In summing up his paper Dr. Uhle asserted that gonorrhea is a really serious disease and one that is readily transmitted to the innocent as well as those guilty of sexual transgressions. It is a disease that is clearly to be classed as being distinct from the minor ailments for which custom permits the retail druggist to sell a variety of drugs known as household remedies.

Dr. Uhle believes that the retail druggist's only available excuse for recommending, or even selling, any of the usual remedies for gonorrhea, aside from the filling of physicians' prescriptions, is that he is unaware of the really serious nature of this disease, and his only warrant in offering this excuse is that his preceptor did it before him.

Dr. E. E. Montgomery, in opening the general discussion, confined his remarks to the consideration of "The Infection of the Innocent and the Suffering and Misery that is Entailed." In his introductory remarks

he expressed the opinion that if gonorrhea could be limited to the vile and the vicious it might be considered as being a beneficient agent, but, unfortunately, this disease is most prone to attack the innocent, and here, being oft times unrecognized, because unsuspected, it usually causes great damage before it is brought under control.

Dr. Montgomery briefly outlined a number of ways in which innocent and unsuspecting persons might be inoculated with this really dread disease and graphic

ally portrayed the sufferings, more horrible than

death, that are in store for a trusting woman who is unfortunate enough to be wedded to a man with a latent or chronic gonorrhea, the result, all to frequently, of the improper treatment accorded him at the hands of the retail druggist.

In concluding his remarks he asked whether, with such an array of conditions that are possible as the sequelae of an improperly treated case of gonorrhea, any number of men would be willing to stultify themselves by risking the happiness, health and even the lives of innocent persons for the meagre profit that

might accrue from the illegal prescribing for diseases

of this type.

Dr. Geo. E. de Schweinitz in speaking of "Gonorrheal Ophthalmia and Its Relation to Total and Partial Blindness" said that the pharmacist no less than the physician must on occasion assume the role of instructor, to prevent the unnecessary spread of disease, and to do this he must himself possess or seek the necessary information. The doctor then briefly reviewed the various types of purulent infections of the eye and called particular attention to the really serious nature of this condition.

He particularly warned retail druggists to refrain from selling eye lotions for sore eyes in the new born, as this condition is almost invariably due to a gonorrheal infection of the mother, and, unless properly treated, is sure to result in total blindness.

In conclusion he begged his hearers to bear the ever present possibility, of gonorrheal infection of the eye and the resulting blindness, in mind and not to contribute, either directly or indirectly, to the increase of this really horrible affliction.

Dr. Thomas Neilson spoke of "The More Remote Complications of Gonorrhea in the Male" and referred particularly to the difficulty of effecting a cure in a patient who had been improperly treated and was

suffering from latent or chronic gonorrhea.

He emphasized the fact that a patient thus afflicted was particularly dangerous in that he was a prolific source of infection to others, without himself being aware of the damage he was doing.

The subject was further discussed by a number of members and visitors who were present and it was unanimously agreed that it would be well to endeavor to have the information presented at this meeting reach even a larger audience. On motion A. J. Stuadt, Dr. Henry Beates, Jr., and Prof. Henry Kraemer were appointed a committee to secure copies of the several communications, and, if practicable, have them reprinted in pamphlet form for generel distribution among retail druggists.

NEW REMEDIES.

A committee of the New York State Ph. A., consisting of Thos. J. Keenan, Willis P. Gregory and Geo. C. Diekman, submitted the following at the 1907 meeting:

(Continued from page 46.)

Strzyzowk's Mixture is a preparation of iron pyrophosphate, quinine hydrochloride and sodium bromide. Three separate solutions must be made and careful manipulation should be resorted to in order to prevent precipitation. The formula is: sodium bromide, 8.0; distilled water 40.0; syrup of orange peel, 20.0; alcohol, 10.0. Dissolve and add the following solution: Quinine hydrochloride, 1.0; distilled water, 40.0; syrup of orange peel, 20.0; mix and add a warm solution of the following: Iron pyrophosphate and ammonium citrate, 4.0; distilled water, 40.0. The whole is mixed and another portion of 40 Gm. of syrup of orange peel added. The dose is a teaspoonful two or three times daily after the principal meals.

Subeston is a basic aluminum diacetate which is used as an antiseptic, astringent and deodorant for infected wounds.

Sulfogenol is a preparation which has the therapeutic characteristics of ichthyol, without its disagreeable | odor and taste. It is prepared by Lüdy & Co. (Burgdorf, Switzerland), from an oil which is obtained from bituminous shale. A certain proportion of sulphur is added synthetically, and it is submitted to a long process of purification. Sulfogenol is a clear, syrupy fluid, of a reddish brown color, and neutral reaction. It is soluble in water, diluted alcohol and in equal parts of water, alcohol or ether. In equal parts of alcohol and ether it does not form a clear solution. Evaporated to dryness at 100 degrees C., it leaves a residue of 40 per cent. At higher temperatures it clears, leaving a little ash. It contains 12 to 13 per cent. of sulphur. It may be dispensed in solutions, ointments, suppositories, pills, etc.

day until a teaspoonful has been taken. Manufactured by Schimmel & Co. (Fritzsche Brothers), Miltitz, near Leipzig, Germany.

Tanphenyform is a moist, brown granular powder of slight aromatic odor and taste. It is composed of 63.9 per cent. of tannin albuminate, 8.3 per cent. of hexamethylenamine, 27.8 per cent. of phenyl salicylate. It is insoluble in water and acids, but is split up by alkaline solutions, so that its components are set free in the intestinal tract. Made and marketed by William R. Warner & Co., Philadelphia, Pa.

Theolactine is a double salt of theobromine sodium and sodium lactate, which forms a fine, white powder containing about 57 per cent. of theobromine. It is very soluble in water and its solutions have a somewhat bitter alkaline taste. It is best given in wafers in doses of 15 grains three or four times daily. It must be protected against light and moisture. Made by Zimmer & Co., Frankfort-on-Main, Germany.

Theonacet has been adopted as a shorter trade name for the well-known theobromine sodium acetate.

Thiodin is a chemical combination of ethyl iodide and thiosinamin. It is said to contain 46.49 per cent. of iodine in organic combination. It forms white crystals soluble in water and difficultly soluble in alcohol. It is used in the indications in which its component substances are used, hypodermically or in pill form.

Thionol is the name of an odorless ichthyol preparation mentioned by a Japanese skin specialist in one of the dermatological journals.

Tincture of Olive Leaves, prepared from the dried leaves of oleae europaeae, has been proposed for use as a febrifuge and anti-periodic in the place of tincture of cinchona. It is made by exhausting the leaves with 60 per cent. alcohol, and the dose is 15 to 30 drops. An extract of the fresh leaf has also been proposed, the dose of which is about 5 drops.

Trypsin, the active proteolytic enzyme of the pancreas, has been recently recommended for the treatment of cancer. The juice of the pancreas contain four fer(1) trypsin, a proteolytic ferment; (2) amylopsin, a diastatic or amylolytic ferment; (3) steapsin, an emulsifying or fat-splitting ferment; (4) a milkcurdling ferment, allied to the rennet of the stomach. Trypsin is given in doses of 15 minims of a 2 per cent. strength hypodermically, the strength being increased by 5 minims every other day, preceded by a few drops of one-tenth of a grain of eucaine solution. The investigators have not gone beyond a 4 per cent. strength of trypsin. Made and marketed in the United States by Fairchild Brothers & Foster, under the name of Injectio Trypsin.

Utrogene is a liquid thymol compound, being diphenylaminthymol, a preparation of the same general characteristics as arhovin. Marketed by A. Voswinkel, Berlin, Germany.

Valinervin is the name given to an effervescent valerian bromide, which is said to be a useful soporific. Vinopyrine has been mentioned anew in recent literature. It is a white crystalline powder, soluble in

about 25 parts of water, which is recommended in doses of 12 to 20 grains, three to four times a day in the treatment of neuralgias, migraine, rheumatism, etc. It is an analogue of citrophene, being a combination of paraphenetidin with tartaric acid.

Virilin is a compound syrup of thyme containing potassium guaiacolsulphonate and calcium hypophosphite, made by G. & R. Fritz, Vienna.

Weissol is the name of a preparation recommended in influenza, coryza, and other cattarrhal affections, by snuffing up the nostrils and blowing into the throat. Its active ingredients are said to consist of a hypophosphite and a peroxide, but definite particulars are lacking.

Xanol is a chemical compound of caffeine, sodium and sodium salicylate, the latter made from the natural oil of gaultheria, which forms a white powder very soluble It is used in water, but decomposed in acid solutions.

as a vasomotor heart tonic, its indirect action being to promote free diuresis. It is made and marketed in 1 oz. cartons at $1.00 an ounce, by the William S. Merrell Chemical Company, Cincinnati, Ohio.

Zyol has been introduced as a competing product with lysoform and formaldehyde soap solutions. It is placed on the market in two forms xyol purissimum and xyol purum. The latter is intended as a general disinfectant. A soap powder containing 10 per cent. xyol has been introduced under the name kaliol. Made by Chem. Fabrik Flick, Ichendorf, Germany.

The Loafer.

BY M. E. HATHAWAY.

Who is it holds the store-box down-
The biggest nuisance in the town?
His name is but a common noun,
The loafer.

Who tells a yarn-the biggest yet-
One fact with many fancies set-
But for the lies has no regrets?
The loafer.

Who all the latest gossip knows
Regarding both his friends and foes?
But chiefly of himself he blows,
The loafer.

Who lets his wife earn all the bread-
The wife who works with hand and head?
And wonders why she ever wed,
The loafer.

Who is it smokes and chews and spits,
Regardless of the thing he hits
While in the grocery store he sits?
The loafer.

And who-with no more days to spoil
Will ne'er be missed and none would foil
His plans to shuffle off this coil?
The loafer.

-[Exchange.

Having Never Told a Lie, George Washington decided not to write his autobiography.-[POOR RICHARD, JUNIOR.

BOARDS OF PHARMACY.

The N. C. Bd. Ph. will meet at Morehead City, July 7, instead of July 6, as was the first plan. The secretary is F. W. Hancock, Oxford.

Oklahoma.-At a special meeting of the Oklahoma State Board of Pharmacy, held in Muskogee December 16 and 17, 1907, out of a class of eight, the following named persons were granted registration on diploma: B. F. Lewin, Stroud, Okla., Imperial University, Kazan, Russia; Claud H. Small, McAlester, Okla., Charleston, Va., College of Pharmacy; H. P. Kennedy, New Berne, N. C., Shaw University, Pharmacy Department; Ernest C. Klein, Cincinnati, Ohio, Cincinnati College of Pharmacy.

Kentucky New Pharmacists.

Chas. Y. Abbott, Louisa, Ky.; Walter J. Dempsey, Newport, Ky.; Edward C. Farrell, Ludlow, Ky.; Jos. Warren Hall Jr., Cincinnati, O.; Edward H. Hinkebein, Louisville, Ky.; Atlee W. Johnston, Olaton, Ky.; Thos. Fred Kiefer, Petersburg, Ind.; Walter McNair, Cincinnati, O.; Joseph J. Magoto, Versailles, Ky.; Val Meinhart Jr., Ashland, Ky.; Chas. J. Meinburg Jr., St. Bernard, Ohio; R. Mitchell Meredith, Dwight, Ill.; James Leslie Moore, Sacramento, Ky.; E. Hugh Morris, Bowling Green, Ky.; Edward D. Morrison, Louisville, Ky.; Emil F. Nehring, Covington, Ky.; Lawson J. Oxley, Cynthiana, Ky.; Glenn E. Perry, Owingsville, Ky.; Robert W. Porter, Pleasureville, Ky.; John M. Poynter, London, Ky.; Herman Schuler, Covington, Ky.; John L. Steele, Ashland, Ky.; John P. Tarbeck, Covington, Ky.; Claude T. Wallace, Paducah, Ky.; Julius Wm. Warns, Louisville, Ky.; Chester Duff, Chavies, Ky.; Chesterfield C. Spearing, Cincinnati, O.; Wm. T. Atkinson, Paintsville, Ky.; Harry G. Gansz, Covington, Ky. The next examination will be held in Louisville, April 14. Applications should be filed with the secretary of the Board, J. W. Gayle, Frankfort, at least ten days before the time of meeting.

New Jersey newly registered pharmacists.

Kelso Carter Ackley, Camden, N. J.; Eugen Donato Di Paolo, Jersey City, N. J.; Sanval Feitsen, Town of Union, N. J.; Jesse A. Fowler, Lakewood, N. J.; Alexander Gumberg, New York, N. Y.; Carl Edward Hoffman, Newark, N. J.; Morris Kanner, Jersey City, N. J.; William Kehoe, Montclair, N. J.; John J. Lane, Jersey City, N. J.; Samuel Lavigne, Newark, N. J.; William T. Lins, New York, N. Y.; John Fraser Mackey, Vineland, N. J.; Joseph Anthony Mauro, Montclair, N. J.; Charles Edward Phelps, Tuxedo Park, N. Y.; Antonio Ricca, Philadelphia, Pa.; Harry J. Schroeder, Paterson, N. J.; Bruno H. Schubert, Town of Union, N. J.; James A. Stanton, Paterson, N. J.; William Henry Ward, New York, N. Y.; Alexander R. Webster, Jamaica, N. Y.

Registered Assistants.

David Breen, Atlantic City, N. J.; Milton Hart Cunningham, Hightstown, N. J.; LaVerne English, West Mansfield, Ohio; Harriet Fox, Rockaway, N. J.; Louis Herman Galluba, Belleville, N. J.; Roland Hurd Kilborn, South Orange, N. J.; Silas C. Law, Orange, N. J.; John Francis McAnulty, Philadeiphia, Pa.; James Charles Nixon, Jersey City, N. J.; John Rigg, Burlington, N. J.

The next examination will be held in Trenton on Thursday and Friday, April 16 and 17.—[HENRY A. JORDEN, Secy., Bridgeton.

Honor and Reputation are two distinct things. Men have honor but lack reputation, while many a man of reputation is devoid of honor. Honor grows in the garden of the heart; reputation grows in the commons of public opinion, and there it often appears as a worthless weed.

PURE FOOD AND DRUGS LAW.

Food Inspection Decisions 84 and 85.

Amendments to Regulations 17 and 19.-The Board of Food and Drug Inspection recommends that Regulations 17 and 19 of the Rules and Regulations for the Enforcement of the Food and Drugs Act of June 30, 1906, be amended to read as follows, such amendments to become and be effective at the date of issue:

Misbranding. Regulation 17. Label. (Section 8.)

sign" or "device" applies to pictorial matter of every description, and to abbreviations, characters, or signs for weights, measures, or names of substances.

(e) An article containing more than one food product or active medicinal agent is misbranded if named after a single constituent.

In the case of drugs the nomenclature employed by the United States Pharmacopoeia and the National Formulary shall obtain.

(b) The principal label shall consist, first, of all information which the food and drugs act, June 30, 1906, specifically requires, to wit, the name of the place of manufacture in the case of food compounds or mixtures sold under a distinctive name; statements which show that the articles are compounds, mixtures, or blends; the words "compound," "mixture," or "blend,” and words designating substances or their derivatives and proportions required to be named in the case of foods and drugs. All this information shall appear upon the principal label, and should have no intervening descriptive or explanatory reading matter. Second, if the name of the manufacturer and place of manufacture are given, they should also appear upon the principal label. Third, preferably upon the principal label, in conjunction with the name of the substance, such phrases as "artificially colored," "colored with sulphate of copper," or any other such descriptive phrases necessary to be announced should be conspicuously displayed. Fourth, elsewhere upon the principal label other matter may appear in the discretion of the manufacturer. If the contents are stated in terms of weight or measure, such statement should appear upon the principal label and must be couched in plain terms, as required by Regulation 29.

(c) If the principal label is in a foreign language, all information required by law and such other information as indicated above in (6) shall appear upon it in English. Besides the principal label in the language of the country of production, there may be also one or more other labels, if desired, in other languages, but none of them more prominent than the principal label, and these other labels must bear the information required by law, but not necessarily in English. The size of the type used to declare the information required by the act shall not be smaller than 8-point (brevier) capitals: Provided, That in case the size of the package will not permit the use of 8-point type, the size of the type may be reduced proportionately.

(d) Descriptive matter upon the label shall be free from any statement, design, or device regarding the article or the ingredients or substances contained therein, or quality thereof, or place of origin, which is false or misleading in any particular. The term "de

Regulation 19. Character of Name. (Section 8.) (a) A simple or unmixed food or drug product not bearing a distinctive name should be designated by its common name in the English language; or if a drug, by any name recognized in the United States Pharmacopoeia or National Formulary. No further description of the components or qualities is required, except as to content of alcohol, morphine, etc.

(b) The use of a geographical name shall not be permitted in connection with a food or drug product not manufactured or produced in that place, when such name indicates that the article was manufactured or produced in that place.

(c) The use of a geographical name in connection with a food or drug product will not be deemed a misbranding when by reason of long usage it has come to represent a generic term and is used to indicate a style, type, or brand; but in all such cases the State or Territory where any such article is manufactured or produced shall be stated upon the principal label.

(d) A foreign name which is recognized as distinctive of a product of a foreign country shall not be used upon an article of domestic origin except as an indication of the type or style of quality or manufacture, and then only when so qualified that it can not be offered for sale under the name of a foreign article.

Labeling of Bitters.-In section 6 of the food and drugs act, of June, 30, 1906, the term "drug," as defined in the act, includes "all medicinal preparations recognized in the United States Pharmacopoeia or National Formulary for internal or external use and any substance or mixture of substances intended to be used for the cure, mitigation, or prevention of disease in either man or other animals."

Notwithstanding this comprehensive definition, it appears from a large correspondence on this subject that there is still some uncertainty as to whether or not certain commodities should be classed as drug products, and of this type are the alcoholic products known as bitters."

It is necessary to determine definitely whether or not "bitters," for example, are to be classed as drugs. This is necessary for the reason that under section 8 of the food and drugs act a drug is deemed misbranded "if the package fails to bear a statement on the label