The Touchstone of Life: Molecular Information, Cell Communication, and the Foundations of Life

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Oxford University Press, 1999 M01 7 - 384 páginas
No one can escape a sense of wonder when looking at an organism from within. From the humblest amoeba to man, from the smallest cell organelle to the amazing human brain, life presents us with example after example of highly ordered cellular matter, precisely organized and shaped to perform coordinated functions. But where does this order spring from? How does a living organism manage to do what nonliving things cannot do--bring forth and maintain all that order against the unrelenting, disordering pressures of the universe? In The Touchstone of Life, world-renowned biophysicist Werner Loewenstein seeks answers to these ancient riddles by applying information theory to recent discoveries in molecular biology. Taking us into a fascinating microscopic world, he lays bare an all-pervading communication network inside and between our cells--a web of extraordinary beauty, where molecular information flows in gracefully interlaced circles. Loewenstein then takes us on an exhilarating journey along that web and we meet its leading actors, the macromolecules, and see how they extract order out of the erratic quantum world; and through the powerful lens of information theory, we are let in on their trick, the most dazzling of magician's acts, whereby they steal form out of formlessness. The Touchstone of Life flashes with fresh insights into the mystery of life. Boldly straddling the line between biology and physics, the book offers a breathtaking view of that hidden world where molecular information turns the wheels of life. Loewenstein makes these complex scientific subjects lucid and fascinating, as he sheds light on the most fundamental aspects of our existence.
 

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The touchstone of life: molecular information, cell communication, and the foundations of life

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The biophysicist from Woods Hole Institute explains cellular communication and the role of information theory in molecular biology, tying together the most recent discoveries in an interesting and ... Leer comentario completo

Contenido

PART TWO INFORMATION FLOW INSIDE CELLS
111
PART THREE INFORMATION FLOW BETWEEN CELLS
165
PART FOUR THE SCIENCE OF THE PECULIAR
323
Epilogue
335
Appendix A Brief Chronicle of Information
337
Recommended Reading
341
References
344
Index
360
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Página 4 - But if we conceive a being whose faculties are so sharpened that he can follow every molecule in its course, such a being, whose attributes are still as essentially finite as our own, would be able to do what is at present impossible to us.
Página 4 - Now let us suppose that such a vessel is divided into two portions, A and B, by a division in which there is a small hole, and that a being, who can see the individual molecules, opens and closes this hole, so as to allow only the swifter molecules to pass from A to B, and only the slower ones to pass from B to A. He will thus, without expenditure of work, raise the temperature of B and lower that of A, in contradiction to the second law of thermodynamics.

Acerca del autor (1999)

Werner R. Loewenstein was Professor of Physiology and Director of the Cell Physics Laboratory at Columbia University and is presently Director of the Laboratory of Cell Communication at the Marine Biological Laboratory, Woods Hole, Massachusetts. He lives in Woods Hole and Key Biscayne, Florida.

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