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that relating to General Pathology, those chapters treating of the bacteria, deserve special mention; and in the part on Special Pathology, all changes occurring in the various organs (excepting those of special sense and the skin) are exhaustively described. The various conflicting theories of the present day also receive just consideration in the chapters on Bacteriology and Neuro-pathology. Among the numerous illustrations are many in colors, rare specimens of the printer's art. The publisher in this volume shows his usual skill, both as to the general arrangement of the text and the quality of the printing. This book, as soon as it becomes better known, will meet with a cordial reception on the part of every student, as well as instructor, in their college work.

C. S.

THIS work is one of grand proportions, and must excite the admiration of all anatomists. In every respect it seems to meet every demand which

could be made of a text-book or reference work on the subject. The text is accurate, concise and clearly put; in matter of detail it leaves nothing obscure. The illustrations are superb, and aid materially in making the text easily understood. They have. been introduced very generously, and are, one and all, of real use-none are introduced from historic motives. The purpose of the work as a whole seems to be characterized by that happy quality which is termed "practical." The publishers have added in this book a new monument to their already long list. It is handsomely gotten up indeed. Taken as a whole, Morris' Anatomy is magnificent-its merits the profession and students of America will not be slow to appreciate. We predict for it a prominent place as a text-book in our medical schools.

HUMAN ANATOMY. A Complete Systematic Treatise. By various authors, including a special section on surgical and topographical anatomy. Edited by HENRY MORRIS, M. B, London. Illustrated by 790 wood-cuts, nearly all of which are original and made expressly for this work by special artists; more than 200 printed in colors. Second edition, revised and enlarged. Philadelphia: P. BLAKISTON'S SONS & CO., 1898. Price, $6.00.

H.

IN this little book Dr. Gottheil has handled the subject of skin cancers in a most practical manner, and has given a very complete exposition of the

subject in all its bearings. The matter of diagnosis is thoroughly covered and made clear. Treatment is given especial attention, and is the important feature of the work; in it he explains in detail the caustic method with which he had such remarkable success. The book is handsomely gotten up in cloth, the illustrations are excellent, the text is clean and clear. It is a book which should reach all the profession.

TREATMENT OF SKIN CANCERS. By W. S. GOTT-
HEIL, M. D., Professor of Dermatology at the N-w York
School of Clinical Medicine; Dermatologist to the Lebanon
Hospital, the North-Western and West Side German Dis-
pensaries, etc. New York: THE INTERNATIONAL JOUR-
NAL OF SURGERY CO., 100 William street. Price, $1.00.

THIS is a master work on diagnosis, having perhaps the largest number of readers of any work on this subject ever published, as it has been trans

CLINICAL TEXT-BOOK OF MEDICAL DIAGNOSIS
FOR PHYSICIANS AND STUDENTS, By OSWALD
VIERORDT, M.D., Professor of Medicine at University of
Heidelberg, etc. Authorized Translation, with Additions, by
FRANCIS H. STUART, A. M., M.D., Member of Medical
Society of County of Kings, New York, etc. Fourth Ameri-
can Edition from Fifth German, Revised and Enlarged. With
194 Illustrations. Pp. 603. Philadelphia: W. B. SAUND-
ERS, 1898.

lated from the German into English, Italian and Russian. It is standard in every sense of the word, being in fact the embodiment of all that is known of value in the science and art of diagnosis. The successive editions indicate its appreciation by

the profession, and its English translation by Dr. Stuart is especially exact. It is a book that is of service at all times, and by reason of its complete index can be used as a ready reference work, as well as a volume for study and reflection. Saunders has improved upon its features as a book-the size and shape being now in conformity with other standard works published by him. Every physician needs this remarkable work in his library. F. P. N.

THE non-operative treatment of hemorrhoids is of interest to every practicing physician. This distressing disorder has generally been recognized as

THE OFFICE TREATMENT OF HEMORRHOIDS, FIS-
TULA, ETC., WITHOUT OPERATION; Together with
Remarks n the Relation of Diseases of the Rectum to other
Diseases in Both Sexes, but especially in Women, and the
Abuse of the Opera ion of Colotomy. By CHARLES B.
KELSEY, A.M, M.D., Late Pro essor of Surgery at the New
York Post-Graduate Medical School and Hospital; Fellow of
the New York Academy of Medicine, etc 12 mo., clth, pp.
68. Price, 75 cents, net. 1898. New York: E. R. PELTON,
Publisher.

belonging distinctly to the surgical domain, and Dr. Kelsey fails to convert us to another faith. It would seem that he himself believes in radical measures save in exceptional cases, and in this respect the title of the essay is somewhat misleading. The little book is one that will be found

well worth perusal, even though it fails to give in detail the non-operative treatment of hemorrhoids, and we would recommend it to our readers.

NOTHING succeeds like success. This applies to medical books as well as events in life. Hare seemingly has been

PRACTICAL DIAGNOSIS. The Use of Symptoms in the
Diagnosis of Disease. By HOBART AMORY HARE, M.
D.. Professor of Therapeutics and Materia Medica in the
Jfferson Medical Coll ge of Philadelphia. Third Edition,
Enlarged and Thoroughly Revised. In one Octavo Volume
of 615 pages, with 204 Engravings and 13 Full-page Colored
Plates. Cloth, $4.75, net. Philadelphia and New York:
LEA BROTHERS & CO., Publishers.

the fortunate author of the year, for his books have been in demand. This is the third edition in two years of this valuable book. We have before commented on its usefulness as a bedside book-a working textbook. It is arranged so that the symptoms are portrayed as we

find them in the sick, and from these clinical pictures can be deduced the disease. It is handsomely printed, elaborately illustrated and of suitable size as a "handy working volume." It deserves its popularity.

F. P. N.

THIS handy little volume should fill a long-felt want with every student of histology. It is the author's purpose to here present a book which will

AN EPITOME OF HUMAN HISTOLOGY, for the Use of
Students in Connection with Lectures and Laboratory Work.
By ARTHUR W. WEYSSE. A.M, Ph.D., Instructor in Biol-
ogy, Massachusetts Inst tute of Technology, Boston, U.S.A.
New York, London and Bombay: LONGMANS, GREEN &
CO., 1898.

aid students in histology in the selection and arranging of all their information acquired during their laboratory investigations. All the various tissues of the body are taken in their proper

order, and each tissue or organ is minutely described, all its microscopic elements being enumerated carefully. We have a form of "Quiz Compend," however, without the questions, and an excellent guide and book of ready reference for use with this branch of study. All facts which every student ought to know are here given; these facts are given in brief and clear language, all unnecessary phrases being omitted; and they are so arranged and grouped, that they may be referred to and studied without loss of much time. The book is without illustrations, it being intended to supplement the specimens actually prepared in the laboratory. C. S.

IMPROVEMENT is said to be the order of the age, and it can be justly said that this, the second edition of the above

work, shows decided superiority over the first edition, which appeared about one year ago. While the author deals with a subject which allows no great departures from the well-beaten track of scientific dicta as already laid down by the greater lights in this department of medicine, still there is some room for a display of originality in the way the subject is to be presented to the student of medicine, and this is what has been done in this book. It is a clear, concise epitome of the subject, and amply fulfills the expectations of those who desire a text-book or a reference work. There is some approach to eclecticism in the grouping of drugs into such a class as "specifics;" the pages devoted to the antitoxine treatment of disease are well written and merit special attention.

A TEXT-BOOK OF MATERIA MEDICA, THERAPEU-
TICS AND PHARMACOLOGY. By GEORGE FRANK
BUTLER, Ph.G, M.D., Professor of Materia Medica and
Clinical Medicine in the College of Physicians and Surgeons,
Medical Department of the University of Illinois; Professor
of General Medicine and Diseases of the Digestive System,
Chicago Clinical School; Attending Physician to Cook
County Hospital, etc. Philadelphia: W. B. SAUNDERS,
925 Walnut street. 1898.

G.

To Our Exchange Friends.-Many of our exchanges still come to us addressed to our old Olive-street home. A two-year's residence in the Trust Building, during which frequent requests for revision were made, and the change to our present quarters make the correction imperative; without it the post-office is greatly inconvenienced, and we suffer from delays. We value our exchanges, we do not want a single number to fail to reach us. Won't you kindly give it a moment's attention and substitute Suite 312, Century Building, for what you now have on your address list? This applies to our advertising patrons as well.

PAPERS for the Original department should be in hand one month in advance, and contributed to THE MEDICAL FORTNIGHTLY exclusively. A liberal number of extra copies will be furnished authors, and reprints may be obtained at reasonable rates, it request accompanies the manuscript. Engravings from photographs furnished free. Contributions, books and exchanges should be sent to the Managing Editor, Century Building, St. Louis. Signature of contributor, for reproduction, should be sent with every article, on a separate slip; use heavy ink, and allow autograph to dry without applying blotter.

COLLABORATORS.

LEWIS H. ADLER, Jr., M. D., Philadelphia.

CHARLES W. BURR, M. D., Philadel-
phia.

DİLLON BROWN, M. D., New York.
HENRY T. BYFORD, M. D., Chicago.
J. K. BAUDUY, M. D., St. Louis.
A. V. L. BROKAW, M. D., St. Louis.
M. V. BALL, M. D., Warren, Pa.
ARCHIBALD CHURCH, M. D., Chicago.
W. T. CORLETT, M. D., Cleveland.
N. S. DAVIS, JR., M. D., Chicago.
FRANK R. FRY, M. D., St. Louis.
LANDON CARTER GRAY, M. D., New
York.

J. N. HALL, M. D., Denver.

HOBART A. HARE, M. D., Philadelphia.

CHAS. O. JEWETT, M. D., Brooklyn.
F. J. LUTZ, M. D., St. Louis.
FRANKLIN H. MARTIN, M. D., Chi-
cago.

J. M. MATHEWS, M. D., Louisville.
E. E. MONTGOMERY, M. D., Philadel-
phia.

ERNEST SANGREE, M. D., Nashville.
NICHOLAS SENN, M. D., Chicago.
A. J. C. SKENE, M. D., Brooklyn.
FERD. C. VALENTINE, M. D., New
York.

EDWIN WALKER, M. D., Evansville.
REYNOLD W. WILCOX, M. D., New
York.

W. E. WIRT, M. D., Cleveland.

H. M. WHELPLEY, M. D., St. Louis.
HUBERT WORK, M. D., Pueblo.

WE

Clinical Lectures

Late Epistaxis in Typhoid Fever.

BY PROF. J. M. DA COSTA, M. D.,

PHILADELPHIA.

Clinic held in Pennsylvania Hospital.

E have here two cases showing this rather rare symptom. The first had a severe epistaxis after he had been ill twenty-nine days, and the temperature had reached normal. The bleeding was violent, lasting half an hour, and the patient losing several ounces of blood. His cerebral symptoms were relieved by the bleeding, and he has been doing very well since.

The second man had bleeding when admitted toward the close of the third week of the disease. On the ninth day after admission there was another profuse bleeding. Here then was late epistaxis occurring in the fourth week, after the symptoms of typhoid fever had practically ceased. This is rare, and is more apt to occur after severe cerebral symptoms which are thus relieved. It is generally caused by deterioration of the blood, during the course of the disease, which may be profoundly altered. If epistaxis occurs early in the disease it is of no harm, and may be of service in relieving some of the accompanying symptoms. If it occurs well on in the disease it need not be noticed, unless severe. If this is the case cold applied to the bridge of the nose, and ergot internally will generally check it. When occurring late in the disease iron is indicated for the deteriorated blood.

Re-enforcement of the Bromides in Treating Epilepsy.

BY PROF. F. X. DERCUM, M. D.,

PHILADELPHIA.

Professor of Neurology, Jefferson Medical College.

Reported Especially for the Medical Fortnightly.

HE treatment of epilepsy depends on a detailed study of the viscera and

made and the diet regulated, digestive disturbances corrected, the skin made active, and exercise in the open air prescribed, comes the question of drugs.

The bromides are the most efficient class of remedies but often do better when varied by or associated with other drugs. Of the bromides themselves I prefer the bromide of ammonium as being the least depressing in its effects. Antipyrin associated with the bromides increases their activity. It will often be found that fifteen grains of the bromide combined with antipyrin will be as effective as thirty or thirty-five grains if used alone._| have seen no injurious effect following the use of antipyrin in this way. To help guard against the mental depression and eruption which may follow a long use of the bromides alone they may be combined with the various iodides with advantage. Trional and sulphonal have also been used during the last four years. Sulphonal is effective in preventing attacks of epilepsy at night. Five to twelve grains often causes a cessation of nocturnal seizures, and sometimes as a further result those during the day also. Another drug used with great success sometimes is antifebrin, given in doses of four to six grains after meals. This sometimes controls the attacks where all other remedies have failed. Then again in other cases it seems to have absolutely no effect. It is thought that the antifebrin acts as a germicide and thus prevents fermentation and is an antiseptic for the stomach. But why should its effects on the stomach and bowels influence epileptic atIt may influence the blood by clearing the alimentary canal of substances which if absorbed would vitiate it. It is known that when skatol and indol and other substances of like nature are plentiful in the system the attacks are more frequent. In this way constipation always favors the course of the disease. Gastro-intestinal atony also contributes its effects. These considerations give reasons for the frequent bathing, exercise, outdoor life, etc., which are so effectual in treating the disease, the excretion of these effete matters being thus aided.

Illegitimate manufacturers are those who attempt to carry water on both shoulders, using in the secular press the testimonials procured from physicians (who gave them in good faith), and advertising their remedies to the laity for self-medication. I place such an house in the same category with the advertising quack doctor, who preys upon the susceptible public. -American Medical Journalist.

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