Handbook of Stem CellsAnthony Atala, Robert Lanza Academic Press, 2012 M12 31 - 1074 páginas New discoveries in the field of stem cells increasingly dominate the news and scientific literature revealing an avalanche of new knowledge and research tools that are producing therapies for cancer, heart disease, diabetes, and a wide variety of other diseases that afflict humanity. The Handbook of Stem Cells integrates this exciting area of life science, combining in two volumes the requisites for a general understanding of adult and embryonic stem cells. Organized in two volumes entitled Pluripotent Stem Cells and Cell Biology and Adult and Fetal Stem Cells, this work contains contributions from the world’s experts in stem cell research to provide a description of the tools, methods, and experimental protocols needed to study and characterize stem cells and progenitor populations as well as a the latest information of what is known about each specific organ system.
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Contenido
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Chapter
40 Stem Cells Derived from Amniotic Fluid | 463 |
Chapter
41 Update on Stem and Progenitor Cells Isolated from Cord Blood | 477 |
Chapter
42 Stem Cells in Extraembryonic Lineages | 481 |
Chapter
43 Mesenchymal Stem Cells in Regenerative Medicine | 493 |
Chapter
44 Multipotent Adult Progenitor Cells | 503 |
Chapter
45 Mesenchymal Stem Cells | 513 |
Chapter
46 Stem Cells Derived from Fat an Update | 529 |
Chapter
47 Ontogeny of the Hematopoietic System | 533 |
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Chapter
13 Engineered Proteins for Controlling Gene Expression | 125 |
Chapter
14 Differentiation in Early Development | 139 |
Chapter
15 Developmental Mechanisms of Regeneration | 155 |
Chapter
16 Primordial Germ Cells in Mouse and Human | 179 |
Chapter
17 CellECM Interactions in Repair and Regeneration | 191 |
Chapter
18 Induced Pluripotent Stem Cells | 227 |
Chapter
19 FeederFree and Defined Culture Conditions for hESC Growth | 237 |
Chapter
20 Isolation and Maintenance of Murine Embryonic Stem Cells | 249 |
Chapter
21 Isolation and Maintenance of Primate ES Cells | 255 |
Chapter
22 Embryonic Stem Cells Derivation and Properties | 275 |
Chapter
23 Approaches for Derivation and Maintenance of Human ES Cells Detailed Procedures and Alternatives | 287 |
Chapter
24 Alternate Sources of Human Embryonic Stem Cells | 303 |
Chapter
25 Genetic Approaches in Human Embryonic Stem Cells and their Derivatives Prospects for Regenerative Medicine | 311 |
Chapter
26 Genetic Manipulation of Human Embryonic Stem Cells | 327 |
Chapter
27 Homologous Recombination in Human Embryonic Stem Cells | 339 |
Chapter
28 Derivation and Differentiation of Human Embryonic Germ Cells | 347 |
Chapter
29 Growth Factors and the SerumFree Culture of Human Pluripotent Stem Cells | 357 |
Chapter
30 FeederFree Culture | 365 |
Chapter
31 Surface Antigen Markers | 375 |
Chapter
32 Lineage Marking | 383 |
Chapter
33 Genomic Reprogramming | 393 |
Chapter
34 Microarray Analysis of Stem Cells and Differentiation | 399 |
Chapter
35 Potential of ES Cell Differentiation Culture for Vascular Biology | 409 |
Chapter
36 Use of Embryonic Stem Cells to Treat Heart Disease | 415 |
Chapter
37 Embryonic Stem Cells in Tissue Engineering | 427 |
Chapter
38 Zebrafish and Stem Cell Research | 439 |
Front Cover | 451 |
Handbook of Stem Cells Volume 2 Adult and Fetal Stem Cells
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Dedication
| v |
vii | |
Foreword | xi |
Preface | xiii |
Contributors | xv |
Chapter 39 The Development of Epithelial Stem Cell Concepts
| 451 |
Chapter
48 Hematopoietic Stem Cells | 553 |
Chapter
49 Cell Therapy for Blood Substitutes | 559 |
Chapter
50 Peripheral Blood Stem Cells | 573 |
Chapter
51 Human Vascular Progenitor Cells | 587 |
Chapter
52 Stem Cells and the Regenerating Heart | 595 |
Chapter
53 Cardiac Stem Cells Biology and Therapeutic Applications | 603 |
Chapter
54 Stem Cells and Heart Disease | 621 |
Chapter
55 Skeletal Muscle Stem Cells | 631 |
Chapter
56 Stem Cells for the Treatment of Muscular Dystrophy | 641 |
Chapter
57 Myoblast Transplantation in Skeletal Muscles | 653 |
Chapter
58 Neurogenesis in the Vertebrate Embryo | 665 |
Chapter
59 The Nervous System | 681 |
Chapter
60 Stem Cells in the Adult Brain | 699 |
Chapter
61 Neural Stem Cells Therapeutic Applications in Neurodegenerative Diseases | 707 |
Chapter
62 Spinal Cord Injury | 723 |
Chapter
63 Sensory Epithelium of the Eye and Ear | 739 |
Chapter
64 Epithelial Skin Stem Cells | 753 |
Chapter
65 Regeneration of Epidermis from Adult Human Keratinocyte Stem Cells | 767 |
Chapter
66 Burns and Skin Ulcers | 781 |
Chapter
67 Stem Cells in the Gastrointestinal Tract | 789 |
Chapter
68 Pancreatic Stem Cells | 819 |
Chapter
69 Adult Progenitor Cells as a Potential Treatment for Diabetes | 827 |
Chapter
70 Islet Cell Therapy and Pancreatic Stem Cells | 835 |
Chapter
71 Cell Therapy of Liver Disease From Hepatocytes to Stem Cells | 855 |
Chapter
72 Adult Liver Stem Cells | 873 |
Chapter
73 Cell Lineages and Stem Cells in the Embryonic Kidney | 889 |
Chapter
74 Orthopaedic Applications of Stem Cells | 901 |
Chapter
75 Somatic Cells Growth and Expansion Potential of T Lymphocytes | 915 |
Chapter
76 Designing Tunable Artificial Matrices for Stem Cell Culture | 927 |
Chapter
77 Stem Cell Gene Therapy | 937 |
Chapter
78 Histogenesis in ThreeDimensional Scaffolds | 951 |
Chapter
79 Stem Cells in Tissue Engineering | 965 |
Chapter
80 Ethical Considerations | 973 |
Chapter
81 Stem Cell Research Religious Considerations | 981 |
Chapter
82 US Stem Cell Research Policy | 991 |
Chapter
83 Overview of the FDA Regulatory Process | 1001 |
Chapter
84 Its Not About Curiosity Its About Cures | 1021 |
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