The Vaccine Book
The Vaccine Book provides comprehensive information on the current and future world of vaccines. It reveals the scientific opportunities and potential impact of vaccines, including economic and ethical challenges, problems encountered when producing vaccines, how clinical vaccine trials are designed, and how to introduce vaccines into widespread use. Although vaccines are now available for many diseases, there are still challenges ahead for major diseases such as AIDS, tuberculosis, and malaria. The Vaccine Book is designed for students, researchers, public health officials, and
1 online resource (469 pages)
9780080542669, 0080542662
1056077693
Front Cover; THE VACCINE BOOK; Copyright Page; CONTENTS; CONTRIBUTORS; PREFACE; ACKNOWLEDGMENTS; CHAPTER 1. GLOBAL BURDEN OF DISEASE; Part A. The Burden of Vaccine-Preventable Diseases; Part B. Cost Effectiveness of Immunization: Asking the Right Questions; Part C. Potential and Existing Impact of Vaccines on Disease Epidemiology; CHAPTER 2. IMMUNOLOGY; Part A. Basic Immunology of Vaccine Development; Part B. Immunological Requirements for Vaccines to Be Used in Early Life; CHAPTER 3. TRIAL DESIGN FOR VACCINES; Part A. Clinical Development of New Vaccines: Phase 1 and 2 Trials. Part B. Phase 3 Studies of VaccinesCHAPTER 4. ETHICS AND VACCINES; CHAPTER 5. UNDERSTANDING MICROBIAL PATHOGENESIS AS A BASIS FOR VACCINE DESIGN; Part A. Bacteria; Part B. Disease-Oriented Approach to the Discovery of Novel Vaccines; Part C. Immunological Memory and Vaccines against Acute Cytopathic and Noncytopathic Infections; Part D. Parasitic Diseases, with an Emphasis on Experimental Cutaneous Leishmaniasis; CHAPTER 6. Disease States and Vaccines: Selected Cases; Part A. Introduction; Part B. Polio; Part C. Rubella